Champions live opera by investing in opera companies and houses through strategic support and grants to widen its reach.

Provides counselling, support and treatment for young people who use drugs, and for their families, across Bury, Rochdale and East Lancashire.

Funds prostate cancer research and empowers patients to improve quality of life for people affected by the disease.

Provides day care, complementary therapy and hospice at home for people with life-limiting illnesses, plus carers and bereavement support.

Provides specialist palliative and end of life care to adults in Barnsley, along with their families and friends.

Provides an independent online resource of news and reports on companies' human rights impacts worldwide, updated hourly.

Provides a public platform for contemporary art, showing work by young and international artists at its gallery on King's Road in London.

Provides medical treatment, training and equipment for children and young people overseas, including heart operations and cardiac services.

Funds hospice services including children's hospice at home, day hospice, lymphoedema care, inpatient nursing and community palliative nurses.

Provides counselling and support to people with mental, emotional or physical problems in modern society.

Brings trained dogs and people together to help people overcome specific challenges and improve their lives.

A youth work charity providing services to young people aged 8 to 25 across South Bristol.

Funds scientific and medical research into the causes, diagnosis, prevention and treatment of all forms of spinal cord injury, prioritising UK-based research.

A society that promotes and advances pharmacology, including clinical pharmacology, nationally and internationally.

Conducts genome-scale structural chemistry research to relieve human suffering, sharing open access research on structural genomics and computational chemistry for human health.

Provides counselling for children, young people, adults, couples and families, plus domestic abuse prevention, mediation, separation support and community volunteering.

Provides aid to families in personal or social distress and supports local community projects.

Provides a safe place for people to talk round the clock by phone, email, text, letter or in person at a branch, and does outreach at festivals, prisons and schools.

Runs the Yvonne Arnaud Theatre in Guildford, staging its own productions and hosting touring shows from outside production companies.